Session 1:  Introduction and Overviews
Session 1:  (Chair, John Coffin)

Jeffrey Strathern
Welcoming Remarks

* Daria Hazuda
The Discovery of Isentress - From Bench to the Clinic (Abstract)

* John Mellors
The Promise of Pre-Exposure Chemoprophylaxis for HIV Prevention (Abstract)

MONDAY, NOVEMBER 12

Session 2:  Viral Entry
Session 2:  (Chair, John Young)

* Walther Mothes
Live Imaging of Cell-to-Cell Transmission of Retroviruses (Abstract)

Gisela Heidecker
New Retroviral Vectors: Rapid Quantitation of Cell-to-Cell and Cell-Free Infection (Abstract)

* Edward Berger
An Engineered Bifunctional Neutralizing Protein Based on the 2-Step Model of HIV-1 Receptor Engagement: Highly Potent and Broad Activity Against Genetically Diverse Primary Isolates (Abstract)

Amy Jacobs
A Covalent Inhibitor Targeting an Intermediate Conformation of the Fusogenic Subunit of the HIV-1 Envelope Complex (Abstract)

Barry O'Keefe
Anti-HIV Entry Inhibitors from Natural Product Extracts as Potential Microbicides (Abstract)

* Sriram Subramaniam
Electron Tomography of Immunodeficiency Viruses and Structural Mechanisms of Cellular Entry (Abstract)

Session 3:  Nucleic Acid Replication
Session 3:  (Chair, Walter Scott)

* Jeffery Miller
Diversity-Generating Retroelements

* Matthew Weitzman
Cellular Recognition and Modification of Viral DNA (Abstract)

Daniele Fabris
Mapping Binding Sites of Nucleic Acid Ligands Targeting Unique Structural Features of the HIV-1 Polypurine Tract by Tandem Mass Spectrometry (Abstract)

Elio Abbondanzieri
Orientational Dynamics on Substrates Determine Enzymatic Function of HIV Reverse Transcriptase (Abstract)

Stefan Sarafianos
Biochemical Mechanism of HIV-1 Reverse Transcriptase Inhibition and Resistance to Translocation-Deficient RT Inhibitors (Abstract)

B. Christie Vu
Nucleoside Analogs Targeted Against NRTI-Resistant HIV-1 Reverse Transcriptase: Introducing Conformational Strain Through Modified Deoxyribose Rings (Abstract)

Guangwei Yang
Transient Kinetic Studies on the Inhibition Mechanism of Human Immunodeficiency Virus Type 1 Reverse Transcriptase by 4'-Ethynyl D4TTP, a Novel Stavudine Analogue with Improved Anti-HIV Activity and Decreased Cytotoxicity (Abstract)

Derrick Goodman
Viral Fitness vs. Drug Resistance: Susceptibility of K65R and K70E HIV-1 Reverse Transcriptase Mutant Viruses to Tenofovir and the Novel Nucleotide Inhibitor GS-9148 (Abstract)

Stuart Le Grice
Small Molecule Inhibitors of HIV RNase H Function: Structural and Biochemical Analysis (Abstract)

* Alan Engelman
LEDGF/p75 and HIV-1 Integration (Abstract)

* Damian McColl
Patterns of Resistance to First Generation Integrase Inhibitors: An Update on Elvitegravir (GS-9137) (Abstract)

Poster Session

TUESDAY, NOVEMBER 13

Session 4:  Novel Antiviral Strategies
Session 4:  (Chair, Kathleen Boris-Lawrie)

* Xiao-Fang Yu
Distinct Packaging Mechanisms of Human Cytidine Deaminase APOBEC3 Proteins into HIV-1 Virions (Abstract)

Rebecca Russell
Dissection of Interactions Between HIV-1 Vif and APOBEC3 Proteins (Abstract)

Alan Rein
Interactions of Murine APOBEC3 and Human APOBEC3G with Murine Leukemia Viruses (Abstract)

* Susan Ross
The Role of Mouse APOBEC3 in Mouse Mammary Tumor Virus Infection (Abstract)

Daria Hazuda
Identification of New Targets for HIV Therapeutics (Abstract)

Sook-Kyung Lee
A Strongly Transdominant Mutation in HIV-1 Gag Defines a New Drug Target (Abstract)

Christine Clouser
HIV Mutation Rate as a Drug Target (Abstract)

* Robert Schooley
Resistance to Small Molecular Inhibitors of HCV: Similarities and Differences with Those Encountered in HIV Drug Discovery and Development

Yutaka Takebe
Identification of Novel Antiviral Small Molecule Compounds That Block HCV Entry (Abstract)

Session 5:  Biology of Viral Infection
Session 5:  (Chair, Christos Petropoulos)

* Julie Overbaugh
Mechanisms and Correlates of Mother-to-Child Transmission of HIV-1 (Abstract)

Jason Brenchley
Preferential Loss of Th17 CD4 T Cells in the Gastrointestinal Tract of HIV-Infected Individuals (Abstract)

Sarah Palmer
Low-Level Viremia Persists for at Least 7 Years in Patients on Suppressive Antiretroviral Therapy (Abstract)

Masahiro Yamashita
Evidence for Direct Involvement of the Capsid Protein and Host Cell Proteins in HIV Infection of Nondividing Cells (Abstract)

Andrew Rice
Identification of Mechanisms That Regulate HIV-1 Tat Function in CD4+ T Cells and Monocytes/Macrophages (Abstract)

Lin Shen
Dose Response Curve Shape Defines Limits on Inhibitory Potential of Classes of Anti-HIV Drugs (Abstract)

Zandrea Ambrose
Antiviral Interference with HIV-1 Infection of Nondividing Cells (Abstract)

* Ann Palmenberg
Deciphering the Information Content of Viral RNAs (Abstract)

Henry Levin
The LTR-Retrotransposon Tf1 Integrates Specifically into Pol II Promoters (Abstract)

Poster Session

WEDNESDAY, NOVEMBER 14

Session 6:  Assembly, Release, and Processing
Session 6:  (Chair, Judith Levin)

* Karin Musier-Forsyth
Viral Protein-Host Cell Protein Interactions Critical for tRNA^Lys Primer Packaging in HIV-1 (Abstract)

Kathleen Boris-Lawrie
HIV-1-Induced Cell Cycle Arrest Suppresses Host Protein Synthesis and Viral RNA Partitions to Membrane-Bound Ribosomes (Abstract)

Milan Kožíšek
Metallacarboranes as Specific and Potent Inhibitors of HIV Protease and Its Resistant Mutants (Abstract)

Jianbo Chen
The Capsid Proteins from HIV and SIV_mac Can Coassemble into Infectious Mature Cores (Abstract)

Adam Zlotnick
A Diversity of Responses to a Single Family of Small Molecule Effectors of Hepatitis B Virus Capsid Assembly (Abstract)

Anjali Joshi
Host Cell Machinery in Retroviral Gag Trafficking (Abstract)

John Mellors
Closing Remarks