9th Annual Symposium on Antiviral Drug Resistance: Targets and Mechanisms




The following posters will be presented in both poster sessions of the Symposium. Abstracts of the posters have been posted here beginning November 16, 2008.


POSTER 1, Rahm Gummuluru
HIV-1 gp120 Independent Capture of Virus Particles by Dendritic Cells Is Dependent on Incorporation of Lipid Raft-Specific Host Cell Determinants in the Virus Particle (Abstract)

POSTER 2, John Howe
Defining the Structural and Functional Roles of Mutations in gp120 Associated with the Emergence of HIV-1 Clinical Resistance to the CCR5 Antagonist Vicriviroc (Abstract)

POSTER 3, Steven Hatch
Glycosphingolipid Composition of HIV-1 Particles Is a Crucial Determinant for Dendritic Cell-Mediated HIV-1 Trans Infection (Abstract)

POSTER 4, Kristen Kahle
Multiple Modes of Resistance to HIV-1 Entry Inhibitor C37 (Abstract)

POSTER 5, Daniel Leaman
PF-68742 Is a Low Molecular Weight HIV-1 Fusion Inhibitor That Targets gp41 (Abstract)

POSTER 6, Nancy P.Y. Chung
DC-SIGN Determinants Necessary for HIV-1 and Dengue Virus Interactions (Abstract)

POSTER 7, Kathleen Boris-Lawrie
HIV-1 Tat RNA Silencing Suppressor Activity Is Conserved across Kingdoms and Counteracts Translational Repression of HIV-1 (Abstract)

POSTER 8, Judith G. Levin
A New Function for the Nucleic Acid Chaperone Activity of HIV-1 Nucleocapsid Protein in Reverse Transcription: Inhibition of Non-Specific Plus-Strand DNA Synthesis (Abstract)

POSTER 9, Brian Herman
Mechanism of Action and Resistance to PMEO-5-Methyl-DAPy, a Novel Pyrimidine Nucleotide Reverse Transcriptase Inhibitor (Abstract)

POSTER 10, Philip McKenna
Quantitative Assessment of NNRTI Barrier to Resistance Using FACSorting and a New HIV-1 Reporter Cell Line (Abstract)

POSTER 11, B. Christie Vu
Nucleoside Analogs Targeted against NRTI-Resistant HIV-1 Reverse Transcriptase (Abstract)

POSTER 12, Linda Dunn
Mutations in the Thumb of HIV-1 RT Affect RT Stability (Abstract)

POSTER 13, Tatiana Ilina
Characterization of Inhibitor Interaction with the RNase H Domain of HIV-1 Reverse Transcriptase (Abstract)

POSTER 14, Jeffrey DeStefano
Polypurine Tracts (PPTs) Are Designed for High Affinity Binding to Their Cognate Reverse Transcriptases, a Property That Can Be Exploited to Produce Novel PPT-Based Antivirals (Abstract)

POSTER 15, Antonio Acosta
RNase H Cleavage-Mediated Dissociation of Primer-Template by HIV-1 Reverse Transcriptase (RT) Containing M41L, T215Y and M184V Mutations (Abstract)

POSTER 16, Stuart Le Grice
Slide into Action: Dynamic Shuttling of HIV Reverse Transcriptase on Nucleic Acid Substrates (Abstract)

POSTER 17, Robert Brinson
SHAMS — Combining Chemical Modification of RNA and Mass Spectrometry to Examine Polypurine Tract-Containing RNA/DNA Hybrids (Abstract)

POSTER 18, Michal Legiewicz
Identification of Pseudoknot Structures in the RNA Transport Element of Murine LTR Retrotransposon Type D with High Throughput Chemical Probing Modulated with Antisense LNAs (Abstract)

POSTER 19, Yi Wang
Direct Probing of RNA Nuclear Export Motifs by SHAPE and 3D Mass Spectrometry (Abstract)

POSTER 20, Bruno Marchand
Discovery and Characterization of Novel Inhibitors of Foot and Mouth Disease Virus Replicase (Abstract)

POSTER 21, Jacques Kessl
Characterization of the Acetylated-Inhibitor Binding Site in HIV-1 Integrase (Abstract)

POSTER 22, Christopher McKee
A Common Tetramer Interface Important for IN Interactions with DNA Substrates and LEDGF (Abstract)

POSTER 23, Islam Hussein, Na Ni
Selection of the HIV-1 Dimerization Initiation Signal in Cell-Based Systems (Abstract)

POSTER 24, Amit Sharma
HIV-1 Nonsecretory Gag mRNA Partitions to Membrane-Bound Ribosomes in a Signal Sequence-Independent and Translation-Dependent Manner (Abstract)

POSTER 25, Christopher Jones
Inositol Phosphate-Mediated Switch in the Nucleic Acid Chaperone Activity of HIV-1 Gag (Abstract)

POSTER 26, Nicole Gudleski
Stable Tetrameric Complexes of Retroviral Gag Proteins Bound to Viral RNA (Abstract)

POSTER 27, Kayoko Waki
Viral Resistance to PA-457 (Bevirimat), a Novel Inhibitor of HIV-1 Maturation (Abstract)

POSTER 28, Arie Hawkins
3D Structure Determination of the HIV-1 Packaging Signal by High-Resolution Mass Spectrometry (Abstract)

POSTER 29, Muthukumar Balasubramaniam
Studies on the Role of the GGA, Arf and Gas7 Proteins in Retrovirus Assembly (Abstract)

POSTER 30, Abdul Waheed
Mechanism of Anti-HIV-1 Activity of the Cholesterol-Binding Compound Amphotericin B Methyl Ester: Inhibition of Assembly/Release Exhibits Vpu-dependence (Abstract)

POSTER 31, Tiffany Lucas
Factors in MLV Envelope Required for Recruitment to HIV-1 Budding Sites (Abstract)

POSTER 32, Kari Dilley
The LYPSL Motif Acts as a Secondary Late Domain for Rous Sarcoma Virus (Abstract)

POSTER 33, Anna Ilinskaya
Characterization of Elements in HTLV-1 Envelope That Regulate Trafficking (Abstract)

POSTER 34, Kyeongeun Lee
Cell-Cycle Dependent HIV-1 Killing Is Mediated through the Viral Protease (Abstract)

POSTER 35, Narendra Dixit
Modeling the Development of Resistance to Antiretroviral Drugs with Large Genetic Barriers: Timing the Failure of Tipranavir (Abstract)

POSTER 36, Alok Mulky
Molecular Characterization of CPSF6 Domains Required for Antiviral Function (Abstract)

POSTER 37, Taichiro Takemura
Cyclosporine Sensitive Restriction to HIV-1 in HeLa Cells (Abstract)

POSTER 38, Kirsten White
Expanded In Vitro Resistance Profile of the Novel Nucleotide RT Inhibitor GS-9131 and Its Parent GS-9148 (Abstract)

POSTER 39, Barry Johnson
Comparison of Thiocarbamates and Formimidoester Disulfides as Inhibitors of HIV-1 RT (Abstract)

POSTER 40, Donald Burke
Aptamer Inhibition of HIV-1 Reverse Transcriptase Variants: A Synthetic Biology Approach (Abstract)

POSTER 41, Dhivya Ramalingam
Anti-HIV-1 Gag Aptamers Show Potential to Inhibit HIV-1 Release (Abstract)

POSTER 42, Jason Rausch
Dissecting APOBEC3G Substrate Specificity by Nucleoside Analog Interference (Abstract)

POSTER 43, Rebecca LaRue
The Artiodactyl APOBEC3 Innate Immune Repertoire Shows Evidence for a Multi-functional Domain Organization That Existed in the Ancestor of Placentals and Enabled Primatification (Abstract)

POSTER 44, Yeshitila Friew
Intracellular Interactions between APOBEC3G, RNA, and HIV-1 Gag: APOBEC3G Is a Monomer That Forms Multimers in Association with RNA (Abstract)

POSTER 45, Michael Vetter
Differences in APOBEC3G Expression in CD4+ T Helper Lymphocyte Subtypes Modulate vif+ and vif HIV-1 Infectivity (Abstract)

POSTER 46, Vickie Marshall
HIF-1
a-Active Natural Product Extracts with Therapeutic Potential for KSHV Related Disease (Abstract)

POSTER 47, Talapady Bhat
Structural Database Using Semantic Web Concepts to Support Structure-Based Drug Design for AIDS (Abstract)

POSTER 48, Yong-Hui Zheng
Further Characterization of a HIV-1 Resistance Phenotype in a Human T Cell Line (Abstract)

POSTER 49, Sloane Yu
Genetic Diversity in HIV-1 pro-pol Persists in Patients on Suppressive Antiretroviral Therapy (Abstract)

POSTER 50, Francesca Cossarini
Characterization of T69 Insertion Mutant in HIV-1 Subtype C with Partial Suppression of Viremia during NRTI Therapy (Abstract)

POSTER 51, Julie Winsett
HIV Drug Resistance Profiles and Clinical Outcomes in Patients with Viremia Maintained at Very Low Levels (Abstract)

POSTER 52, Evguenia Svarovskaia
Pre-Existing Low-Levels of the K103N HIV-1 RT Mutation Is a Risk Factor for Treatment-Naïve Patients Failing a 3TC+ZDV+EFV Regimen (Abstract)

POSTER 53, Alberto Bosque
Induction of HIV-1 Latency and Reactivation in Primary Memory CD4+ T Cells (Abstract)

POSTER 54, Sunil Arora
Increased Frequency of Drug-Resistance Related Mutations in HIV-1 Subtype-C Isolates in Treatment Naïve Individuals from North India (Abstract)

POSTER 55, Kristie Ibarra
Reduced Ribavirin Antiviral Efficacy via Nucleoside Transporter-Mediated Drug Resistance (Abstract)

POSTER 56, Mingjie Zhang
ß-estradiol Attenuates the Anti-HIV-1 Efficacy of Stavudine (D4T) in Primary PBL (Abstract)




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