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In the schedule below, click on a session title to go to that particular session.  Keynote talks are designated with an asterisk.  Abstracts of the talks and posters have been posted here beginning November 15, 2009.

SUNDAY, NOV 15 6:00-7:40 pm Oral Session 1:
Introduction and Overviews
MONDAY, NOV 16 8:30-10:10 am Oral Session 2:
Viral Entry

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10:40 am-3:10 pm Oral Session 3:
Nucleic Acid Replication

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3:40-5:20 pm Oral Session 4:
Integration

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6:00-7:30 pm Poster Session 1
TUESDAY, NOV 17 8:30 am-12:00 noon Oral Session 5:
Novel Antiviral Strategies

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1:30-6:00 pm Oral Session 6:
Assembly, Release, and Processing

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6:00-7:30 pm Poster Session 2
WEDNESDAY, NOV 18 8:30 am-12:20 pm Oral Session 7:
Biology of Viral Infection



SUNDAY, NOVEMBER 15

Session 1:  Introduction and Overviews
Session 1:  (Chair, John Mellors)

Jeffrey Strathern
Welcoming Remarks


Stephen Hughes
Dedication to David Derse

* Jeffery Taubenberger
Influenza: The Once and Future Virus (Abstract)

* H. Clifford Lane
Immunologic Aspects of HIV Infection


MONDAY, NOVEMBER 16

Session 2:  Viral Entry
Session 2:  (Chair, Charles Boucher)

* Sriram Subramaniam
Structural Mechanisms of HIV Entry (Abstract)

Anna Ilinskaya
Interactions among HTLV-1 Envelope and Cell Proteins and Their Impact on
Virus Infection and Restriction (Abstract)

Adeyemi Adedeji
Identification and Mechanistic Characterization of Novel Inhibitors of
SARS-CoV Entry (Abstract)


* Dimiter Dimitrov
Targeting Virus-Receptor Interactions by Cross-Reactive Human Monoclonal
Antibodies and Engineered Antibody Domains (Abstract)

Session 3:  Nucleic Acid Replication
Session 3:  (Chair, Walter Scott)

Jeffrey Strathern
Mutations That Reduce the Fidelity of Retrotransposition (Abstract)

* Hiroaki Mitsuya
4'-Ethynyl-2-fluoro-2'-deoxyadenosine (EFdA), a Translocation Defective
Reverse Transcriptase Inhibitor with Highly Potent Activity against Diverse
Multi-Drug-Resistant HIV-1 Variants (Abstract)

Michael Parniak
Highly Potent in Vivo Activity of QD Administration of 4'-Ethynyl-2-fluoro
Deoxyadenosine in SIV-Infected Rhesus Macaques (Abstract)

Vinay Pathak
A Novel Molecular Mechanism of Dual Resistance to NRTIs and NNRTIs
(Abstract)

Barry Johnson
Purine-Based NNRTIs Showing High Efficacy and Low Cytotoxicity in Cell
Culture against Multiple NNRTI-Resistance Mutations (Abstract)

* Craig Cameron
New Strategies to Treat and Prevent Viral Infection Revealed from
Studies of Mechanisms of Ribavirin Resistance (Abstract)

* Dan Loeb
Hepatitis B Viruses: The Gymnastics of Genome Replication (Abstract)

Matthias Götte
Single Molecule Studies Reveal Sliding Dynamics of HCV NS5B in
Complex with RNA (Abstract)

Stuart Le Grice
Biochemical and Structural Studies of Novel HIV-1 Ribonuclease H
Inhibitors (Abstract)

Session 4:  Integration
Session 4:  (Chair, Daria Hazuda)

* Frederic Bushman
Integration of HIV DNA: Mechanistic and Therapeutic Implications (Abstract)

Mamuka Kvaratskhelia
Organizations of Individual Subunits within the Fully Functional HIV-1
Integrase Tetramer as a Therapeutic Target (Abstract)

* John Moran
Studies of a Human Transposable Element (Abstract)

David Garfinkel
Posttranslational Interference of Ty1 Retrotransposition by Antisense
RNAs (Abstract)

Poster Session 1 (Posters 1-36)


TUESDAY, NOVEMBER 17

Session 5:  Novel Antiviral Strategies
Session 5:  (Chair, Christopher Aiken)

Catherine Adamson
Functional and Structural Studies on the HIV-1 Maturation Inhibitor
Bevirimat (Abstract)

Yoshihiro Kitamura
Inhibitory Activity of Interferon-Induced Protein 44 and Its Paralog on
Hepatitis C Virus Replication (Abstract)

Jeremy Luban
TRIM5 and the Antiviral State (Abstract)

Vineet KewalRamani
HIV-1 Restriction by a Cyclophilin-Related Factor in Human Cells
(Abstract)

Yasumasa Iwatani
Four Lysine Residues in the APOBEC3G C-terminal Domain Are
Critical for HIV-1 Vif-Mediated Ubiquitination/Degradation (Abstract)

* Kathleen Collins
HIV-1 Infects Multipotent Progenitor Cells Causing Cell Death and
Establishing Latent Cellular Reservoirs (Abstract)

Lisa Jenkins
SAMT Analog Inactivation of HIV-1 Nucleocapsid NCp7: In Vitro
Mechanism and in Vivo Efficacy (Abstract)

* James Cowan
Catalytic Metallodrugs as Inorganic Inhibitors of Virus Replication (Abstract)

Session 6:  Assembly, Release, and Processing
Session 6:  (Chair, Jeremy Luban)

Jianbo Chen
High Efficiency of HIV-1 Genomic RNA Packaging and Heterozygote
Formation Revealed by Single Virion Analysis (Abstract)

* Scott Emr
ESCRT Complexes in Membrane Trafficking (Abstract)

Nicole Gudleski
Building Blocks of Immature Retroviral Particles: Stable Dimeric,
Tetrameric, and Hexameric Gag-Viral RNA Complexes (Abstract)

* John Guatelli
Restriction of HIV-1 Virion-Release by BST-2 and Its Counteraction
by Vpu (Abstract)

Alan Rein
On the Role of RNA in HIV-1 Particle Assembly: Is SP1 an
Allosteric Signal Transmitter? (Abstract)

* Mark Yeager
Structure of Full-Length Hexameric HIV-1 CA: A Molecular Jigsaw
Puzzle Solved by Hybrid Methods (Abstract)

Scott Butler
A New Small Molecule Class of Early Stage HIV-1 Inhibitor That
Targets the Capsid Protein (Abstract)

Christopher Aiken
A Small Molecule HIV-1 Inhibitor That Destabilizes the Viral Capsid
(Abstract)

Peijun Zhang
CryoEM Structure of HIV-1 Capsid Assembly Reveals Novel
Intersubunit Interfaces Critical for HIV-1 Capsid Function (Abstract)

Ruifeng Yang
Functional Analysis of a Novel 3-fold CTD-CTD Interface in the
HIV-1 Capsid (Abstract)

* Celia Schiffer
Molecular Recognition in Enzymes — Proteases and
Resistance / APOBEC3G and Oligomerization (Abstract)

Poster Session 2 (Posters 37-72)


WEDNESDAY, NOVEMBER 18

Session 7:  Biology of Viral Infection
Session 7:  (Chair, Sandra Ruscetti)

* Robert Silverman
Implications for the Retrovirus XMRV in Human Disease (Abstract)

* Ila Singh
Prevalence and Distribution of XMRV in Prostate Cancers and
Other Human Tissues (Abstract)

* Francis Ruscetti
Detection of Infectious Xenotropic Murine Leukemia Virus-Related
Virus (XMRV) in Blood Cells from Patients with Chronic Fatigue
Syndrome (Abstract)

Stuart Le Grice
NCI Response to XMRV

* J. Victor Garcia-Martinez
In Vivo Analysis of HIV Replication and Pathogenesis (Abstract)

* Jeffrey Lifson
Recent Developments in Non-Human Primate Models for AIDS Research (Abstract)

Lina Josefsson
Analysis of HIV DNA Molecules in Single Infected Cells from Recently
and Chronically Infected Patients (Abstract)

Una O'Doherty
Measurement of Total and Integrated HIV DNA May Be a Useful
Indicator of Ongoing Replication (Abstract)

Stephen Hughes
Closing Remarks





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